Tokyo in the near future. A young man, NOUNAI Senri, joins a major pharmaceutical company, RUOWA, to cure his sister, Mari, of an incurable disease. There, he takes RUOWA METAL, a drug that turns muscle into metal, but the side effect is that his brain cells turn to sand, putting his life in danger. He is also forced to kill people suffering from the same side effect. Today is his brother's wedding. He is afraid that his work will be exposed.